Nipple Adenoma: Systematic Review of Literature

Nipple Adenoma: Systematic Review of Literature

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Background:.Nipple adenomas (NAs) are rare benign proliferative tumors presenting as palpable nodules, erosive lesions, or nipple discharge, mimicking other conditions.This systematic review categorizes cases into sole NA (ONA) or co-diagnoses with other conditions (CONA) to enhance clinical recognition, diagnosis, and treatment efficacy.Methods:.

Following PRISMA guidelines, a PubMed search was conducted for NA.Inclusion criteria covered original research, excluding reviews or other breast diseases.Bias risk was assessed through a thorough search, authors independently evaluated studies, and data were synthesized using varied measures.Subgroups ONA and CONA were formed.

Analyses were altitude sunscreen conducted in Excel and R, complemented by a qualitative review due to case report predominance.Biases in case reports were transparently addressed.Results:.Of the 86 studies, 387 cases were analyzed, showing 10.

34% dorisvale station for sale with co-diagnoses of malignant or premalignant conditions.Mean age was 44, with a female predominance (97%).ONA (347 cases) and CONA (40 cases) subgroups exhibited variations in symptoms, physical findings, and imaging.Treatment modalities included excision (51.

39%), biopsy alone (11.1%), and mastectomy (8.6%).Mean follow-up of 56.

73 months revealed recurrence (2.87%) and malignancy development (1.79%), notably in CONA cases (33.33%).

Conclusions:.This study provides insights into the broader age range of NA and its associations.Higher co-diagnosis rates were correlated with older age, highlighting the necessity for thorough investigation, with excision as the primary treatment.Follow-up emphasizes the significance of identifying and monitoring CONA cases, which pose a higher malignancy risk.

Recurrence is presumed to be linked to proper lesion excision and co-diagnosis.